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Novofem HRT Tablets

From   £0.00

Includes free private prescription

Expected Delivery: Tuesday

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Buy Novofem tablets online in the UK

Order Novofem tablets online from Click Pharmacy for safe and reliable hormone replacement therapy. Simply complete a quick online assessment, and if approved by one of our prescribers, your medication will be delivered discreetly to your door.

What is Novofem?

Novofem is a sequential combination hormone replacement therapy (HRT) used to treat symptoms of menopause, such as hot flushes, night sweats, and vaginal dryness. It contains estradiol (oestrogen) and norethisterone acetate (progestogen), and is suitable for women who have a uterus but have not had a natural period in the last six months.

What is Novofem used for?

There are two main uses for Novofem HRT (cyclical HRT) tablets:

Relief for Menopausal symptoms

Novofem is most commonly prescribed to relieve symptoms like:

  • Hot flashes and night sweats
  • Vaginal dryness and discomfort
  • Mood changes like irritability and anxiety
  • Sleep disturbances
  • Reduced sex drive (libido)

If your menopause symptoms are severely impacting your quality of life, white Novofem tablets also help provide relief when lifestyle changes alone are not enough. It is important to note that you have to take it every day without a break and it is normal to gain weight.

Preventing Osteoporosis

Estrogen plays an important role in bone health. During menopause, declining estrogen levels lead to accelerated bone loss. This makes postmenopausal women more vulnerable to developing osteoporosis and fractures.

If you are at high risk for osteoporosis and other osteoporosis medications are not suitable, Novofem is one option to help strengthen bones and prevent bone fractures. The white tablets contain a form of progesterone in both 1mg or 2mg that helps with menopause and prevent osteoporosis.

How does Novofem work?

Novofem works by replacing the hormones your body stops producing after menopause mainly oestrogen and progesterone. It comes as a 28-day treatment cycle with two types of tablets. For the first 16 days, you take red tablets containing estradiol (a form of oestrogen) to relieve symptoms like hot flushes, night sweats, and vaginal dryness.

For the next 12 days, you take white tablets that contain both estradiol and norethisterone acetate (a synthetic progesterone). This helps protect the womb lining from becoming too thick, which can happen if oestrogen is taken alone, and triggers a withdrawal bleed similar to a natural period.

By following this cycle, Novofem mimics your body natural hormone pattern, providing effective relief from menopause symptoms while keeping your uterus healthy.

Novofem ingredients

The active ingredients in Novofem are:

  • Each red tablet contains 1mg of estradiol.
  • Each white tablet contains 1mg of estradiol and 1mg of norethisterone acetate.

Inactive ingredients include:

  • Lactose monohydrate
  • Maize starch
  • Magnesium stearate
  • Titanium dioxide (E171)
  • Propylene glycol
  • Red iron oxide (E172)

For a full list of ingredients, please refer to the Patient Information Leaflet.

Other HRT treatments

Besides Novofem, Click Pharmacy also offers other types of HRT including:

  • Elleste Solo
  • Elleste Duet
  • Elleste Duet Conti Tablets
  • Kliovance
  • Premarin
  • Livial Tablets
  • Premique
  • Evorel Patches
  • Utrogestan

HRT is mainly divided into three types: sequential or cyclical HRT (like Novofem), continuous combined HRT, and oestrogen-only HRT. The best type for you depends on factors like when you had your last period. If you're unsure, consult your GP, one of our pharmacists, or visit our menopause treatments page for guidance.

This page is medically reviewed by:
Name Jana Abelovska - GPhC-Registered Pharmacist
Role Superintendent Pharmacist
GPhc Number 2220953

Novofem dosage

Novofem comes in a 28 day pack. You take:

  • 1 red tablet (estradiol) per day for days 1-16
  • Then 1 white tablet (estradiol + progestogen) per day for days 17-28

How to take Novofem tablet

Take red and white tablets at around the same time each day. Swallow whole with water - do not chew. It is among sequential HRT treatments, which means you need to take it daily.

Start new packs back-to-back without a break for best results. You’ll get a monthly bleed when starting a new pack.

Always follow dosage directions. Taking more tablets than prescribed will not provide extra benefit but may cause side effects.

In case of Novofem shortages or any other HRT shortages, take medical advice from your doctor immediately.

Novofem side effects

Novofem can cause side effects, although not everyone experiences them. It is not unusual to experience side effects when starting Novofem for the first 16 days. You may experience any of the following common side effects:

  • Breast tenderness
  • Headaches
  • Indigestion
  • Nausea
  • Vaginal bleeding
  • Weight gain
  • Swelling in hands/feet

Let your doctor know if any side effects do not resolve within a few months or are severe. Serious risks like blood clots, stroke, endometrial cancer are very rare but also need prompt medical care. Also, it is recommended to take HRT for the shortest amount of time.

Novofem warnings

Before using Novofem, discuss your full medical history and any factors that increase health risks with HRT. There is a chance of having health likes with HRT treatments including Novofem. For example, risks may be higher if you:

  • Have a history of blood clots, stroke, heart disease, liver disease, endometrial hyperplasia or cancer
  • Have uncontrolled high blood pressure
  • Have migraines
  • Have bleeding between periods
  • Are significantly overweight

Combination HRT like Novofem has been associated with a small increased risk of breast cancer and ovarian cancer. So regular follow-up and cancer screening are important after taking Novofem tablets.

The following are some more Novofem risks that you should be aware of and consult your doctor immediately if you experience any:

  • Risk of developing breast cancer
  • Unwanted weight gain
  • Experiencing low mood
  • Fluid retention and bloating
  • Increased risk of developing endometrial cancer
  • Formation of blood clot at any time

Also, be aware that HRT does not prevent memory loss or dementia. There are concerns it may increase risks if started after age 65. If you want to use an alternative like Elleste Duet tablets, which is also suitable for menopausal women, make sure to consult your doctor first.

Novofem in pregnancy and breastfeeding

Do not take Novofem (combined HRT) if you are pregnant or breastfeeding. Inform your doctor right away if you become pregnant while taking Novofem.

Novofem is only for use in postmenopausal women. Additional contraception may be needed within a year of your last period or under age 50. Discuss contraception with your doctor because Novofem while breastfeeding is not generally recommended.

Discreet Delivery

Once your order has been approved, it will be dispatched via Royal mail. All orders are sent using a tracked and signed for service.

Delivery charges

Royal Mail 1st Class | £3.95.  Delivered within 1-3 working days (Excludes Sundays and bank holidays).

Royal Mail Special Delivery Guaranteed before 1pm | £6.95. Delivered within 1 working day before 1pm (Excludes Sundays and bank holidays).  

Free Delivery on orders over £100.

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Further information on return and refunds

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How it works

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

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Expected Delivery: Tuesday

Order before 15:00pm (Monday to Friday) for next day delivery