Premarin Tablets is an effective HRT for menopause. Buy Premarin Tablets from Click Pharmacy today, we have a wide range of HRT available.


6/15/2025 2:07:31 PM


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Premarin Tablets

Premarin is a hormone replacement therapy (HRT) medication used to relieve symptoms of menopause, such as hot flashes, night sweats, and vaginal dryness.

Medication features:

  • Hormone replacement therapy for estrogen deficiency
  • Contains conjugated oestrogens
  • For postmenopausal women

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Expected Delivery: Tuesday

If you order within: 12h36m

Premarin Prices

  • Medicine prices
  • Delivery Information
Medicine 84 Tablets
Premarin 0.3mg £42.99
Premarin 0.625mg £44.99
Premarin 1.25mg £69.99

Prices include free private prescription.

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

Royal Mail 1st Class | £3.95

Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

Find out more about our delivery service.

Refunds and returns – Read further information on return and refunds.

  • Overview
  • Directions
  • Cautions

Buy Premarin Online UK

You can order Premarin online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Premarin

Premarin Tablets are a hormone replacement therapy (HRT) for estrogen deficiency in postmenopausal women. It effectively eases the symptoms of menopause and prevents osteoporosis in postmenopausal women at high risk of future fractures who are contraindicated to or intolerant of other medicinal products approved for the prevention of osteoporosis. Premarin contains conjugated oestrogens, which emulate the female sex hormone oestrogen.

Premarin Tablets are an easy way to ease the life-altering and annoying symptoms of menopause, like hot flushes, strong heartbeat, osteoporosis, dryness of the eyes, mood swings, reduced sex drive, night sweats, vaginal dryness, irritability, insomnia, and pain during sex.

Premarin Summary Information

Type of medicine

Hormone replacement therapy (HRT) medication


Relieves symptoms of menopause

How it works

Contains conjugated estrogens to restore hormonal balance

Active Ingredient

Conjugated Estrogens

Directions of use

Oral tablets, taken as directed by a healthcare professional

Available strengths

0.3mg, 0.625mg, & 1.25mg

Side effects

Common side effects include Headache, breast pain, nausea, diarrhoea, stomach pain, painful joints


Store at room temperature away from light and moisture



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any menopause treatment, including Premarin.

How effective are the Premarin tablets?

Premarin Tablets are effective even at low doses to relieve postmenopausal symptoms. Depending on your condition and where you are in your menopause journey, you may take it short or long-term. It prevents osteoporosis (fragile bones) in women who have had menopause and are most likely to have bone problems.

The drug may also effectively prevent osteoporosis for women with a heightened risk of fractures if they cannot take any other form of prevention medication. This can occur as the bone-strengthening and protecting hormone oestrogen decreases during menopause.  

The effects of the Premarin Tablets kick in relatively quickly, with many women experiencing the benefits within just a few weeks.  

What is contained in the Premarin tablets?

The active ingredient in the Premarin Tablet is conjugated estrogen.

The inactive ingredients are:  

● Lactose Monohydrate (spray dried)
● Microcrystalline Cellulose
● Hypromellose 2208, K100M (100,000 cps)
● Magnesium Stearate

The ingredients in the film-coating material are:

● Sucrose
● Microcrystalline Cellulose
● Hydroxypropyl Cellulose
● Hypromellose, 2910, E6 (6 cps)
● Hypromellose, 2910, E15 (15 cps)
● Polyethylene Glycol 400
The edible ink contains propylene glycol and either titanium dioxide (E171) or iron oxide black (E172).
● The green tablets contain quinolone yellow (E104), indigo carmine (E132) and polysorbate 80.
● The maroon tablets contain red aluminium lake (E129) and indigo carmine (E132).
● The yellow tablets contain quinolone yellow (E104), sunset yellow (E110) and polysorbate 80

In case of any allergic responses, consult your GP or Click pharmacy doctor before going ahead and purchasing your prescription.

How do Premarin tablets work?

Premarin Tablets work by restoring the hormonal balance in the body, reducing or preventing menopausal symptoms from occurring. Hormone Replacement Therapy (HRT) eases the symptoms of menopause by supplementing the levels of hormones that the body can produce naturally.

Premarin Tablets contain conjugated oestrogens, which are natural forms of oestrogen. Suppose you have had a hysterectomy (an operation to remove the uterus) in that case, oestrogen is the only hormone you require to replace.

If you haven’t had your uterus removed, you may be prescribed a progestogen medicine alongside Premarin. When oestrogen levels increases, the lining of the uterus (the endometrium) grows excessively. This will substantially increase the risk of complications like endometrial cancer. If you have not had a hysterectomy, you may be prescribed another medicine that provides combined HRT.


For how long can I use the Premarin tablets?

You may use Premarin Tablets for several years to ease the side effects of menopause. In the UK, the average menopause age in women is 51, though some women start normal menopause as early as 45. Premature menopause would be earlier than this. Menopausal symptoms usually last between 4 and 5 years, so in most situations, HRT may be used during this time.

HRT must only be necessary as a relatively short-term treatment as your body adjusts to menopause. You should review your HRT with your GP at least once each year and have regular gynaecological checkups.

What dose should I choose?

Start with the minimum effective dose for the shortest duration for the initiation and continuation of treatment. Premarin 0.3-1.25 mg daily is the usual starting dose for women without a uterus. Doctors recommend continuous administration.

Premarin Tablets are available in the following strengths:

  • 3 mg pack-contains green oval, biconvex sugar-coated tablets, marked with 0.3, containing 0.3 mg conjugated estrogens
  • 625 mg pack-contains maroon oval, biconvex sugar-coated tablets, marked with 0.625, containing 0.625 mg conjugated estrogens
  • 25 mg pack- contains the yellow oval, biconvex sugar-coated tablets, marked with 1.25, containing 1.25 mg conjugated estrogens

Your doctor will tell you which strength you need to take, depending on your symptoms and risks.

How should I use the Premarin tablets?

Take one tablet daily with a drink, either with or without a meal. Take the tablet at a fixed time daily for the best results. Only take medicine if you remember to take a missed dose within 12 hours; if you remember after it, skip the dose. Do not double up or take two within 12 hours of each other.

Do not take breaks between your packs of Premarin Tablets. However, have your treatment reviewed at least once a year to ensure you are still using the best form of medication and receiving the most significant benefits from it.

Side effects

Apart from the benefits of Premarin Tablets, there are potential side effects. These may be experienced by some women and not by others. Doctors usually recommend waiting at least 12 weeks before changing HRT as your body may get used to the effects of the hormones and balance out. After this time, most women find their side effects disappear. However, you may speak to your doctor anytime if you are concerned.

The potential side effects of the Premarin Tablet are

  • Headache,
  • Migraine,
  • Breast tenderness/pain,
  • Nausea,
  • Bloating,
  • Abdominal pain,
  • Painful joints,
  • Leg cramps,
  • Tingling in the hands or feet,
  • Vaginal bleeding or discharge,
  • Breakthrough bleeding,
  • Leucorrhoea,
  • Thrush,
  • Anxiety,
  • Depression,
  • Changes in libido,
  • Mood swings,
  • Weight loss/gain.

Stop using Premarin Tablets and seek medical attention immediately if you notice early signs of any of the following:

  • Blood clots – pain and swelling of the legs, difficulty breathing
  • Stroke – sudden migraines, blurred vision
  • Heart disease – chest pain which extends to the neck or arm
  • Liver disease – yellow colouration of the skin or eyes.

If these adverse effects bother you or the product affects you in any other way, stop using Premarin immediately and talk to your doctor or pharmacist. You may book a free and confidential appointment with our online specialist at Click Pharmacy anytime.

Other warnings to consider

HRT pose an increased risk of developing breast cancer, endometrium or ovaries. However, Premarin Tablets help to lower this risk in women who have not had their wombs removed.  

Premarin Tablets are not recommended for women with heart disease or a heart attack, as HRT may affect the heart and circulation.

Blood clots may occur in HRT users. The risk of blood clots doubles if you:

  • Ever had breast cancer
  • May have cancer which is sensitive to oestrogen (including uterine cancer)
  • Have untreated endometrial hyperplasia (an excessively thick womb lining)
  • Suffer from a blood clotting disease or have ever had a blood clot
  • Have recently had a heart attack or stroke
  • Have unexplained vaginal bleeding
  • Have a history of liver disease
  • Suffer from porphyria (a rare hereditary blood disease)
  • Are allergic to the ingredients of  the patch
  • Are pregnant or breastfeeding

    Inform your GP if you plan to use Premarin Tablets and have ever had any of the following health complications:

  • Fibroids
  • Impaired liver function
  • Uterine problems, including endometriosis or endometrial hyperplasia
  • Circulation problems (e.g. angina, heart attack)
  • High risk of blood clots
  • Diabetes
  • Migraine
  • Gallstones
  • Systemic lupus erythematosus
  • Asthma
  • Epilepsy
  • Fluid retention
  • High blood pressure
  • High-fat levels in the blood
  • Otosclerosis (a hereditary ear disorder)
  • Low calcium levels in the blood
  • A family history of breast cancer or another oestrogen-sensitive cancer
  • History of severe allergic reactions 

Premarin Reviews

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Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

Next Day

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Price £42.99

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Available strengths:

0.3mg 0.625mg 1.25mg


Price £42.99

Includes free private prescriptions

In stock

2024/06/15 2024/06/16

Order before 15:00pm (Monday to Friday) for next day delivery