Silkis is an effective way of controlling and treating psoriasis. It contains calcitriol as an active ingredient. Buy Silkis today from Click Pharmacy.


7/17/2025 9:12:41 PM


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Silkis Ointment

Silkis is a topical medication used to treat psoriasis, a skin condition characterized by red, itchy, and scaly patches.

Medication features:

  • Used to treat severe plaque psoriasis
  • Contains calcitriol
  • Helps achieve clear and fresh skin

Next Day Delivery Available

UK Registered Pharmacy

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Expected Delivery: Friday

If you order within: 12h36m

Silkis Ointment Prices

  • Medicine prices
  • Delivery Information
Medicine Quantity Price
Silkis Ointment 3 mcg 1 Tube £34.99

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

Royal Mail 1st Class | £3.95

Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

Find out more about our delivery service.

Refunds and returns – Read further information on return and refunds.

  • Overview
  • Directions
  • Cautions

Buy Silkis Online UK

You can order Silkis online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Silkis Ointment

Silkis is used for the topical treatment of mild to moderately severe plaque psoriasis with up to one-third of the body surface area involvement. It contains an active ingredient, calcitriol (a vitamin D derivate) that inhibits and normalizes the unrestrained cell growth in psoriasis affected skin.

Silkis Summary Information

Type of medicine

Topical psoriasis treatment


Treats psoriasis, a skin condition

How it works

Reduces skin cell growth and inflammation

Active Ingredient


Directions of use

Apply directly to affected skin

Available form


Available strengths

3 mcg

Side effects

Common side effects include Skin discomfort, pruritus, erythema, skin irritation, dry skin.



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any eczema and psoriasis treatment, including Silkis.

How effective is Silkis?

Silkis is an effective way of controlling and treating psoriasis. It contains calcitriol as an active ingredient, and it has been scientifically tested and proven to be highly effective in treating psoriasis, helping people to achieve clear and fresh skin.

How does Silkis work?

Silkis ointment contains the active ingredient calcitriol, which is a type of medicine called a vitamin D analogue. Calcitriol is used to treat plaque psoriasis, which is a condition that results in the scaling and thickening of the skin due to excessive skin cell production. Calcitriol reduces the excessive skin cell production by binding to the vitamin D receptors on skin cells called keratinocytes, in the same way as natural vitamin D would bind. This helps to bring the rate at which skin cells are produced back to normal and therefore helps to improve the symptoms of plaque psoriasis.

Name Jana Abelovska
Role Superintendent Pharmacist
GPhc Number 2220953

How should I take Silkis?

Silkis is an ointment for use on the skin only. Always use this medicine exactly as directed by the doctor.  If you are not sure about how to use this medication, feel free to contact CLick Pharmacy with any queries. 

  • Carefully apply the ointment to face since it has a higher risk of the irritation. Avoid contact with sensitive areas like the eyes.

  • After using the ointment, wash hands to prevent the unintentional spread to the non-affected zones.

  • Due to the potential effect on calcium metabolism, the ointment may not be applied under an occlusive wound dressing.

  • In case of the severe irritation or allergic reaction occur, the treatment should be stopped, and contact the doctor immediately.

  • Although no significant hypercalcemia (high blood calcium levels) was observed during the clinical studies with this ointment, there is some absorption of calcitriol by the skin. This gives a risk of an increase of blood or urine calcium levels.

  • Do not swallow this product. If you accidentally do so, seek immediate medical attention. 

  • Regularly follow your treatment, according to strictly to your doctor's advice.

  • If you feel that the effect of this medicine is too strong or too weak, talk to your pharmacist or doctor. 

The risk is minimal if you follow your doctor’s advice. However, if any problem occurs after using the Silkis, then do contact your doctor or physician.

What dose should I chose?

  • There is no experience with the use of Silkis in children. Therefore, Silkis should not be used in children. 
  • Do not use more than 30g of ointment per day, and do not cover more than one-third of skin area, approximately one full leg and the one full arm.

  • Wash your hands after each application in order to avoid any contact with other non-lesioned areas. 

  • Apply a thin layer of Silkis over the affected areas to be treated twice a day, morning and evening, before retiring or as advised by a doctor.

What are the side effects of Silkis?

Silkis have side effects like all other medicines, but not all individuals get them. In case of severe irritation or contact allergy, then treatment should be stopped, and the patient should seek medical attention. If contact allergy is confirmed, then the treatment must be discontinued.

Side effects of the Silkis may take place:

  • Common side effects may be

  • Skin discomfort.

  • Pruritus.

  • Erythema (skin redness).

  • Skin irritation.

  • Uncommon side effects may take place:

  • Psoriasis aggravation.

  • Dry skin.

  • Not known side effects may be

  • Contact dermatitis.

  • Skin oedema.

  • Hypotonia (decrease tension in muscles), lack of appetite, constipation, nausea, vomiting and depression may occur after using too much calcitriol. Therefore, contact your physician if these symptoms appear.

Silkis Ointment Reviews

How to order medications from us

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

Next Day

Add delivery details and complete payment process.

Price £34.99

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Available strengths:

3 mcg


Price £34.99

Includes free private prescriptions

In stock

2024/07/17 2024/07/18

Order before 15:00pm (Monday to Friday) for next day delivery