Duac Gel is used in the treatment of acne and it is available online from Click Pharmacy. Buy Epiduo safely and securely from Click Pharmacy today and start your tre


5/21/2025 12:28:01 PM


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Duac Once Daily

A topical acne treatment containing benzoyl peroxide and clindamycin, it is used once daily to treat acne.

Medication features:

  • Helps overcome acne
  • Clears the infection
  • Brings back natural skin tone and texture

Next Day Delivery Available

UK Registered Pharmacy

Price Match Guarantee

Expected Delivery: Wednesday

If you order within: 12h36m

Duac Once Daily Prices

  • Medicine prices
  • Delivery Information
Medicine 1 tube 3% Gel
Duac Once Daily 30g £29.99
Duac Once Daily 60g £43.99

Prices include free private prescription.

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

Royal Mail 1st Class | £3.95

Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

Find out more about our delivery service.

Refunds and returns – Read further information on return and refunds.

  • Overview
  • Directions
  • Cautions
  • FAQ

Buy Duac Once Daily Online

You can order Duac Once Daily online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Duac Once Daily

Acne is a very common issue with an estimated 80% of people aged between 11 and 30 suffering with an outbreak of it as some point. It can be highly distressing and can affect the confidence of the sufferer as well as being extremely painful in some cases.

The powerful double action of Duac’s active ingredients can help you to overcome your acne struggles, clearing the infection from within and bringing back your natural skin tone and texture.

Duac Once Daily Summary Information

Type of medicine

Acne treatment


Treats acne vulgaris

How it works

Helps unclog pores and reduce inflammation

Active Ingredient


Directions of use

Apply a thin layer to affected areas once daily

Available strengths

30g, 60g

Side effects

Common side effects include Skin irritation, Dryness, Redness, sensitivity to sunlight



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any acne treatment, including Duac Once Daily.

How effective is Duac?

Duac contains two powerful active ingredients called clindamycin phosphate and benzoyl peroxide. Together they are designed to effectively treat the bacterial infection by breaking down the comedones, the black and white heads, which will, in turn, unblock the glands.

The two ingredients, when working together, are known to be highly effective in dealing with acne, with 50% of blemishes clearing up in as little two weeks in some cases where Duac is applied. It has also been shown to remove nearly double the number of blemishes than it’s closest acne-fighting competitor and 10% more by the end of the first month of use.

Why choose Duac?

Duac is a popular choice because it only needs to be applied once a day, making it an easy treatment to use. It is also preferable for anyone who does not wish to take tablets, as the skin is still getting the benefit of an antibiotic without the need to swallow a pill.

Another reason for its popularity is that together, the ingredients can remove nearly all acne bacteria on the skin, clearing it up and easing the discomfort of outbreaks in a matter of weeks. In fact, Clindamycin, the antibiotic contained in Duac, is the number one antibiotic used for clearing up acne in the UK. One major reason for this is that the other antibiotic sometimes prescribed for acne can stain teeth, whereas Clindamycin does not.

What is contained in Duac?

Duac is a gel which contains two active ingredients; an antibiotic designed to kill the bacteria causing the acne called clindamycin and an acne-fighting antiseptic called benzoyl peroxide.

How does Duac work?

Clindamycin is widely used to fight many bacteria-based infections, including Propioni bacterium acnes, the bacteria which feeds on the sebum produced within the skin’s sebaceous glands. This bacteria produce fatty acids and waste products, which begin to irritate the glands causing them to become inflamed and erupt into acne-like spots. The application of clindamycin controls the number of bacteria able to survive on the skin, thus stopping the irritation and inflammation and allowing the skin to heal.

The medication fighting alongside the antibiotic in Duac is benzoyl peroxide which is a keratolytic, a medicine designed to break down the protein forming part of the structure of the skin known as keratin. The application of this antiseptic breaks down skin cells, causing them to shed and break down the comedones, also known as blackheads and whiteheads with it. This then clears the sebaceous glands, which means fewer comedones can be formed.

Duac gets to work in as little 48 hours with the clindamycin killing bacteria which causes the acne, and then any bacteria left behind is then cleared up by the antibacterial benzoyl peroxide.

Name Jana Abelovska
Role Superintendent Pharmacist
GPhc Number 2220953

How should I take Duac?

Duac is designed to be used once a day, in the evening. It is important to wash the skin with a mild cleanser before applying the gel to ensure the skin is as clean as possible.

The treatment must be applied in a thin layer to all affected areas of the skin rather than only on specific spots.

It is important to apply sparingly. If the gel is difficult to rub in, you have used too much.

How long can I take Duac for?

Duac is known to get to work within 48 hours, and results can be seen from as little as two weeks. It is important to persevere with the treatment but to discontinue use after 12 weeks to give the skin a break.

To avoid your acne coming back after you stop using the treatment, you may be advised to use a 2% to 4% benzoyl peroxide product for a minimum of a week after your stop Duac.

What are the side effects of Duac?

Different people will react in different ways when using a product such as Duac but the most common side effects of the gel can include:

  • dryness
  • itching
  • redness
  • mild peeling of the skin
  • a burning sensation

If you experience any major side effects, including severe redness, burning or stinging, or excessive peeling, then stop the treatment and consult with your Click Pharmacy doctor or GP.

In some rare cases, the antibiotic can get into the body’s digestive system, where it will do its job of killing all bacteria there aside from Clostridium difficile, which can trigger diarrhoea. If you experience diarrhoea, stop using the treatment and book an appointment with your doctor that day to discuss your next steps. You can book a free and confidential online appointment with the doctors at Click Pharmacy at any time.

Other warnings to consider

Duac’s ingredients can bleach clothing and towels, so be aware of what you put on when using it and when drying your face.


Can I go out in the sun while using Duac Gel?

Using Duac Gel makes your skin more sensitive to the sun. You should try to avoid exposure to the sun. you should always wear sunscreen with an spf of at least 30.

Duac Once Daily Reviews

How to order medications from us

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

Next Day

Add delivery details and complete payment process.

Price £29.99

Price Checker


Available size:

30g 60g


Price £29.99

Includes free private prescriptions

In stock

2024/05/21 2024/05/22

Order before 15:00pm (Monday to Friday) for next day delivery