Malarone is a trusted malaria tablet that works 1-2 days after starting you course. Buy Malarone from Click Pharmacy today.


6/23/2025 3:37:34 PM


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Malarone 250mg/100mg Tablets

Malarone is a prescription medication used for malaria prevention and treatment.

Medication features:

  • A prescription medication
  • A combination of drugs called atovaquone and proguanil
  • Treats and prevents malaria

Next Day Delivery Available

UK Registered Pharmacy

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Expected Delivery: Tuesday

If you order within: 12h36m

Malarone Prices

  • Medicine prices
  • Delivery Information
Medicine 1 week 2 week 3 week 4 week 8 week 12 week
Malarone Generic £39.99 £64.99 £92.99 £124.99 £244.99 £349.99
Malarone Brand £39.99 £64.99 £92.99 £124.99 £244.99 £349.99

Prices include free private prescription.

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

Royal Mail 1st Class | £3.95

Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

Find out more about our delivery service.

Refunds and returns – Read further information on return and refunds.

  • Overview
  • Directions
  • Cautions
  • FAQ

Buy Malarone Online UK

You can order Malarone online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Malarone

Malarone is the brand name for a combination of drugs called atovaquone and proguanil. It’s used in the treatment and prevention of malaria, a potentially fatal disease caused by parasites passed on from female mosquitoes which carry the malaria infection. The mosquitoes pick up the infection from the blood of infected humans, so protecting yourself from malaria can also help to stop the spread of malaria in the areas you are travelling in.

Atovaquone doesn’t work on its own; as such, it’s always paired with proguanil for optimum results as they work in two separate ways to stop malarial parasites in the blood stream from reproducing and developing.

Malarone Summary Information

Type of medicine

Antimalarial medication


Prevents and treats malaria by killing the malaria parasite in the bloodstream

How it works

Contains a combination of atovaquone and proguanil, which inhibit different stages of the malaria parasite's lifecycle

Active Ingredient

Atovaquone, Proguanil

Directions of use

Take orally once a day, starting one or two days before entering a malaria-endemic area and continued daily during the stay and for seven days after leaving the area

Available strengths

250mg, 100mg

Side effects

Common side effects include Vertigo, upset stomach, diarrhoea, headaches, feeling weak, vomiting, nausea



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any anti-malarial treatment, including Malarone.

Who is at risk of malaria?

Anyone who travels through, stays at or lives in a country with malaria transmission is at risk of malaria and especially children, pregnant women and those travelling from countries without malaria. The malaria most commonly associated with life-threatening symptoms is Plasmodium falciparum, which is found in Africa.

Malarone is specifically used to prevent the spread of this type of malaria and is especially used in areas where the parasite is resistant to other medicines, such as chloroquine.

How effective is Malarone?

Malarone is one of the three most widely used medicines given to people travelling in high risk areas. It is particularly useful for preventing malaria in areas where this parasite is resistant to other antimalarial medicines, such as chloroquine.

Its effectiveness can be diminished if taken on an empty stomach as the body cannot absorb as much of the drug as well as if you are sick within one hour of taking it. If this occurs, it is important to take another dose right away to ensure you receive the required amount for prevention or treatment of malaria.

What are the advantages of taking Malarone?

Malarone has a number of advantages for travellers to high risk areas. It can be started within 2 days of travel meaning it is useful for last minute plans and upon your return, you need only take it for 7 days rather than 4 weeks like some other antimalarials.

In areas where malaria is an endemic, non immune travellers (those who are travelling from countries without malaria) showed a far lower adverse effect to treatment with Malarone and it is also approved for use in children travelling to high risk areas.

How does Malarone work?

The malaria causing parasite needs a certain enzyme to multiply, and the proguanil present in Malarone targets this enzyme and blocks it. At the same time, atovaquone interferes with the parasite’s reproductive process, making it almost impossible for the infection to take hold and spread.

Malarone alternatives

You can find various anti-malarial tablets that act as alternatives to Malarone. For instance:

  • Doxycycline
  • Lariam (mefloquine)

In addition to these treatments, you should practice mosquito bite prevention to minimise the risk of contracting the disease.


What dose should I choose?

An adult tablet of Malarone contains 250mg of atovaquone and 100mg of proguanil hydrochloride.

If you are using the drug to protect yourself from infection, you should take one tablet a day starting one or two days before you are scheduled to arrive in an area where there is a risk of malaria. Continue taking the medicine for the duration of your stay and for another week after you leave.

  • Malarone tablets contain 100mg proguanil and 250mg atovaquone. They are suitable for preventing malaria in adults and children weighing more than 40kg, and for treating malaria in adults and in children weighing between 11kg and 40kg.
  • Malarone paediatric tablets contain 25mg proguanil and 62.5mg atovaquone. They are suitable for preventing malaria in children weighing between 11kg and 40kg, and for treating malaria in children between 5kg and 11kg.

You can get more information on dosages by speaking to your GP or by contacting the medical professionals here at Click Pharmacy.

How should I take Malarone?

For optimal absorption, the tablets should be consumed with a fatty meal or a glass of milk, and you should take them at the same time each day.

Side effects

You are likely to experience a number of side effects from using Malarone Tablets. These side effects should not stop you from taking this drug, as the side effects of Malaria are far more dangerous than the side effects of this drug. Common side effects include the following:

  • Vertigo
  • Upset stomach
  • Diarrhoea
  • Headaches
  • Feeling weak
  • Vomiting
  • Nausea/feeling sick
  • Feeling tired

Do I need to take Malarone Tablets once I have returned from an infected area?

You should continue to take Malarone Tablets for up to a week after returning from an infected area.

Can pregnant or breastfeeding women use Malarone Tablets?

Pregnant or breastfeeding women should not avoid taking Malarone Tablets. This is because the risk of malaria to the mother and baby is far more dangerous than the interaction of this drug.

Malarone Reviews

How to order medications from us

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

Next Day

Add delivery details and complete payment process.

Price £39.99

Price Checker


Available strengths:

Generic Brand


Price £39.99

Includes free private prescriptions

In stock

2024/06/23 2024/06/24

Order before 15:00pm (Monday to Friday) for next day delivery