Orlistat 120mg

Medication features:

  • Used in the treatment of obesity
  • Generic version of Xenica
  • For people who are classed as medically obese


Available strengths:

120 mg


Price £32.99

Includes free private prescriptions

In stock

Delivery Time


Expected delivery date:

Wednesday, 13 December 2023

If you order within:


Next Day Delivery

Next Day

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  • Overview
  • FAQ
  • Side Effects
  • Patient Information Leaflet
  • Reviews

What is Orlistat 120mg

Orlistat is the generic version of Xenical and it is used in the treatment of obesity. The drug is designed for people who are classified as medically obese, meaning they have a body mass index (BMI) of over 30. It can also be used by people with a BMI of over 28 who also have health complaints that are related to weight, such as high blood pressure and diabetes.

The treatment reduces the amount of fat that the body absorbs from food and for the best results, it should be used in conjunction with lifestyle and dietary changes.

Why choose Orlistat?

For some people, obesity is an everyday struggle and conventional methods of weight loss, like dietary changes and an increase in activity levels, are not enough. By altering the way your body processes fat, Orlistat can help you to keep your weight under control and improve your figure. In turn, this may boost your confidence and raise your overall quality of life. The treatment can also enhance your health by reducing your risk of a range of weight-related medical complaints, including diabetes, stroke and certain cancers.

Can I buy Orlistat online?

Orlistat is a weight loss treatment which has been approved for sale online. It was originally approved in its branded form, known as Xenical, before the generic version, Orlistat, came on to the market. You can arrange a free and confidential consultation online with one of our doctors at Click Pharmacy, who can then assess your suitability for the product before drawing up a prescription and sending your medication to you direct by Next day Delivery where possible.

How Effective Is Orlistat?

Clinical trials of Orlistat showed that in just 12 weeks, 67% of the participants had lost 5 % of their body weight through the use of Orlistat alongside healthy eating and increased activity. 62% went on to lose 10% after 12 months.

Usually, within around 24 hours, the body begins excreting excess fat from food through bowel movements, and it is this process which enables users to lose 50% more weight than if they were simply using a balanced lifestyle plan of increased exercise and lower calorie eating alone.

What dose should I choose?

3 tablets should be taken over the course of the day, and any more than this has not been shown in trials to make any further difference to weight loss.

Dosage instructions are provided with the treatment, and if you have any questions on this subject, you can get in touch with your doctor or consult our specialists at Click Pharmacy.

How should I take Orlistat?

Orlistat capsules, which contain 120mg of the active ingredient, are usually taken three times a day with water immediately before, during or shortly after meals that contain fat, though the tablets must be taken within an hour of eating.

You need not to take a capsule if you do not eat, or else if you eat a meal deficit in fat as, for the medication to work, 30% of each meal needs to contain fat.

How does Orlistat work?

Orlistat works by acting as a lipase inhibitor, attaching to the enzymes which break down the fat in your food, so the body cannot absorb them. In other words, it reduces the amount of fat that your body keeps within it by up to 30%, passing out, instead, through your stools. By reducing fat intake in this simplified way, it makes it easier to not only lose the weight in the first place but to also maintain the loss once you have reached your target goal. However, to achieve the best possible results, it is important to make lifestyle changes too. These may include eating more healthily, cutting down on alcohol consumption and doing more exercise.

As Orlistat is designed to block fat from being absorbed, it can also make it harder for your body to absorb certain important vitamins. As such, it is important to take a fat-soluble multivitamin at least 2 hours before or after taking an Orlistat tablet each day. This supplement should include vitamin A, D, E, K and beta carotene.

What are the side effects of Orlistat?

The side effects most commonly associated with Orlistat include abdominal discomfort, sweating, nausea, loss of appetite, wind accompanied by an oily discharge, a sudden need to open the bowels and oily or liquid stools.

Such side effects tend to occur in the first 2 weeks of taking the medication as the body gets used to the effects of Orlistat. It is advised that you speak to your GP or a doctor at Click Pharmacy if these symptoms persist or worsen after this time.

Despite the fact that you are taking a medication designed to stop the absorption of fat, it is not recommended to continue eating an unhealthy and high-fat diet because this can lead to unpleasant gastrointestinal side effects also.

If you would like additional information about these potential symptoms, you can contact your doctor or speak to our experts.

How Long do I take Orlistat before I notice a difference?

With the body no longer absorbing such a large amount of fat in each of your meals, you instead start to use and burn off the fat already stored in your body for your day-to-day energy usage.

So, depending on the other lifestyle changes you make, Orlistat should make a difference to your weight loss within around 2 weeks and can help you in losing around 5% of your body weight within 12 weeks.

Can I drink alcohol while taking Orlistat?

Alcohol does not interact with Orlistat so that you can consume alcoholic beverages whilst on Orlistat. However, note that alcohol contains many calories and can significantly impact the weight loss journey. It may be redundant to consume alcohol while trying to lose weight unless you drink moderately. In addition to this, the effects of alcohol can have an effect on your decision-making skills when eating and snacking.

Should I skip meals whilst taking Orlistat?

Be sure to eat all meals whilst on Orlistat. Maintaining a balanced diet and avoiding unhealthy, unnecessary snacking is crucial. This is because skipping meals does not result in weight loss and can cause severe malnutrition instead. The best way to lose weight healthily is to eat throughout the day. In fact, your breakfast should be the largest meal of the day, while the other meals of the day should be portioned.

What is the key difference between Orlistat, Xenical and Alli?

Objectively, it seems like Orlistat, Xenical, and Alli are for the same purpose. However, there are slight differences between the three.

First, Orlistat is a weight loss medication. It works by significantly reducing the absorption of fat from the diet. Orlistat is the generic version of Xenical. Xenical is the brand name version of Orlistat. Xenical contains around 120 mg of Orlistat in each capsule, equivalent to the 120 mg capsules of Orlistat. Simply put, Orlistat and Xenical are medically equivalent and interchangeable. The key difference between the two is that Orlistat is relatively cheaper as it is the generic version of the treatment.

On the other hand, Alli is a different brand of medication. Alli also contains the active ingredient Orlistat. However, it differs because it only contains 60 mg of Orlistat in each capsule. It is a low dose of Orlistat used during the initial stages of treatment. Additionally, it is preferred as it can reduce the likelihood of severe side effects.

The lower dose of Orlistat, 60 mg in Alli, is ideal for overweight individuals (BMI 28+). Similarly, the higher dose of Orlistat, 120 mg in Xenical and Orlistat, is meant for obese individuals (BMI 30+).

Alternatives to Orlistat

As mentioned, Orlistat is the most affordable option. However, some patients prefer to use the brand name version of Orlistat, known as Xenical. Xenical functions exactly like Orlistat and even contains the same amount of active ingredients as Orlistat. However, it is more expensive.

If you do not wish to turn to medicinal treatments, you can try healthy diets and exercise plans for weight loss as an alternative.

Should I take a dose of Orlistat Tablets if I skip a meal?

If you skip a meal, you should also skip your dose of Orlistat Tablets. Taking Orlistat Tablets on an empty stomach can cause serious harm to the body.

Why do I have to take Orlistat Tablets after consuming a fat-containing meal?

It is important to take Orlistat Tablets after consuming a fat-containing meal. This is because Orlistat Tablets work by targeting the fat consumed with meals, if you have not consumed a meal the active ingredient could target the wrong type of fat and cause harmful side effects.

Do I need to take any supplement while using Orlistat Tablets?

It is recommended to take supplements such as vitamins which contain vitamins A, D, E and K while using Orlistat Tablets. This is because there is a possibility that Orlistat Tablets interfere with the absorption of these vitamins.

Can I use Orlistat Tablets for weight loss if I am diabetic?

Orlistat Tablets are suitable for use for diabetic patients however it is advised to regularly check your blood sugar levels. This is because there is a possibility that Orlistat Tablets interfere with blood sugar levels.

Can I combine other drugs with Orlistat Tablets?

Using Orlistat Tablets may stop medication used to treat seizures and fits. You should consult with a GP or pharmacist before combining these drugs.

Like all medicines, you may experience a number of side effects from using Orlistat Tablets. Common side effects include:

  • Increased bowel movements
  • More urgent bowel movements
  • Changes in bowel function
  • Poor bowel and bladder control

If any of these side effects worsen you should stop using Orlistat Tablets and seek medical advice, from a GP or pharmacist, as soon as possible.

Always read the patient information leaflet before starting your treatment. The patient information can be found here.

Authored by

Last reviewed 11 April 2023

Superintendent Pharmacist GPhC No.2220953

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