Orlistat is a proven weight loss treatment and works by blocking some of the fat that you eat, keeping it from being absorbed by your body. Buy Orlistat from Click P


6/23/2025 4:10:32 PM



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Orlistat 120mg Tablets

Orlistat is a weight loss medication, primarily used to aid in weight loss by blocking the absorption of dietary fats in the intestine.

Medication features:

  • Used in the treatment of obesity
  • Generic version of Xenica
  • For people who are classed as medically obese

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Expected Delivery: Tuesday

If you order within: 12h36m

Orlistat Prices

  • Medicine prices
  • Delivery Information
Medicine Quantity Price
Orlistat 120 mg 42 tablets £32.99
Orlistat 120 mg 84 tablets £57.99
Orlistat 120 mg 168 tablets £94.99
Orlistat 120 mg 252 tablets £139.99

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

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Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

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  • Overview
  • Directions
  • Cautions
  • FAQ

Buy Orlistat Online UK

You can order Orlistat online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Orlistat 120mg

Orlistat is the generic version of Xenical and it is used in the treatment of obesity. The drug is designed for people who are classified as medically obese, meaning they have a body mass index (BMI) of over 30. It can also be used by people with a BMI of over 28 who also have health complaints that are related to weight, such as high blood pressure and diabetes.

The treatment reduces the amount of fat that the body absorbs from food and for the best results, it should be used in conjunction with lifestyle and dietary changes.

Orlistat Summary Information

Type of medicine

Weight loss medication


Helps in weight loss by blocking the absorption of dietary fats in the intestine

How it works

Restricts the action of lipase enzymes, reducing the absorption of fats in the digestive system

Active Ingredient


Directions of use

Take orally with meals containing fat, up to three times a day

Available strengths

120 mg

Side effects

Common side effects include abdominal pain, flatulence, fatty or oily stools, itching, back pain



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any weight loss treatment, including Orlistat.

Why choose Orlistat?

For some people, obesity is an everyday struggle and conventional methods of weight loss, like dietary changes and an increase in activity levels, are not enough. By altering the way your body processes fat, Orlistat can help you to keep your weight under control and improve your figure. In turn, this may boost your confidence and raise your overall quality of life. The treatment can also enhance your health by reducing your risk of a range of weight-related medical complaints, including diabetes, stroke and certain cancers.

How effective Is Orlistat?

Clinical trials of Orlistat showed that in just 12 weeks, 67% of the participants had lost 5 % of their body weight through the use of Orlistat alongside healthy eating and increased activity. 62% went on to lose 10% after 12 months.

Usually, within around 24 hours, the body begins excreting excess fat from food through bowel movements, and it is this process which enables users to lose 50% more weight than if they were simply using a balanced lifestyle plan of increased exercise and lower calorie eating alone.

How does Orlistat work?

Orlistat works by acting as a lipase inhibitor, attaching to the enzymes which break down the fat in your food, so the body cannot absorb them. In other words, it reduces the amount of fat that your body keeps within it by up to 30%, passing out, instead, through your stools. By reducing fat intake in this simplified way, it makes it easier to not only lose the weight in the first place but to also maintain the loss once you have reached your target goal. However, to achieve the best possible results, it is important to make lifestyle changes too. These may include eating more healthily, cutting down on alcohol consumption and doing more exercise.

As Orlistat is designed to block fat from being absorbed, it can also make it harder for your body to absorb certain important vitamins. As such, it is important to take a fat-soluble multivitamin at least 2 hours before or after taking an Orlistat tablet each day. This supplement should include vitamin A, D, E, K and beta carotene.

What is the key difference between Orlistat, Xenical and Alli?

Objectively, it seems like Orlistat, Xenical, and Alli are for the same purpose. However, there are slight differences between the three.

First, Orlistat is a weight loss medication. It works by significantly reducing the absorption of fat from the diet. Orlistat is the generic version of Xenical. Xenical is the brand name version of Orlistat. Xenical contains around 120 mg of Orlistat in each capsule, equivalent to the 120 mg capsules of Orlistat. Simply put, Orlistat and Xenical are medically equivalent and interchangeable. The key difference between the two is that Orlistat is relatively cheaper as it is the generic version of the treatment.

On the other hand, Alli is a different brand of medication. Alli also contains the active ingredient Orlistat. However, it differs because it only contains 60 mg of Orlistat in each capsule. It is a low dose of Orlistat used during the initial stages of treatment. Additionally, it is preferred as it can reduce the likelihood of severe side effects.

The lower dose of Orlistat, 60 mg in Alli, is ideal for overweight individuals (BMI 28+). Similarly, the higher dose of Orlistat, 120 mg in Xenical and Orlistat, is meant for obese individuals (BMI 30+).

Alternatives to Orlistat

As mentioned, Orlistat is the most affordable option. However, some patients prefer to use the brand name version of Orlistat, known as Xenical. Xenical functions exactly like Orlistat and even contains the same amount of active ingredients as Orlistat. However, it is more expensive.

If you do not wish to turn to medicinal treatments, you can try healthy diets and exercise plans for weight loss as an alternative.

Name Jana Abelovska
Role Superintendent Pharmacist
GPhc Number 2220953

What dose should I choose?

3 tablets should be taken over the course of the day, and any more than this has not been shown in trials to make any further difference to weight loss.

Dosage instructions are provided with the treatment, and if you have any questions on this subject, you can get in touch with your doctor or consult our specialists at Click Pharmacy.

How should I take Orlistat?

Orlistat capsules, which contain 120mg of the active ingredient, are usually taken three times a day with water immediately before, during or shortly after meals that contain fat, though the tablets must be taken within an hour of eating.

You need not to take a capsule if you do not eat, or else if you eat a meal de?cit in fat as, for the medication to work, 30% of each meal needs to contain fat.

How long do I take Orlistat before I notice a difference?

With the body no longer absorbing such a large amount of fat in each of your meals, you instead start to use and burn off the fat already stored in your body for your day-to-day energy usage.

So, depending on the other lifestyle changes you make, Orlistat should make a difference to your weight loss within around 2 weeks and can help you in losing around 5% of your body weight within 12 weeks.

Should I skip meals whilst taking Orlistat?

Be sure to eat all meals whilst on Orlistat. Maintaining a balanced diet and avoiding unhealthy, unnecessary snacking is crucial. This is because skipping meals does not result in weight loss and can cause severe malnutrition instead. The best way to lose weight healthily is to eat throughout the day. In fact, your breakfast should be the largest meal of the day, while the other meals of the day should be portioned.

Side effects

Like all medicines, you may experience a number of side effects from using Orlistat Tablets. Common side effects include:

  • Increased bowel movements
  • More urgent bowel movements
  • Changes in bowel function
  • Poor bowel and bladder control

If any of these side effects worsen you should stop using Orlistat Tablets and seek medical advice, from a GP or pharmacist, as soon as possible.

Do I need to take any supplement while using Orlistat Tablets?

It is recommended to take supplements such as vitamins which contain vitamins A, D, E and K while using Orlistat Tablets. This is because there is a possibility that Orlistat Tablets interfere with the absorption of these vitamins.

Can I use Orlistat Tablets for weight loss if I am diabetic?

Orlistat Tablets are suitable for use for diabetic patients however it is advised to regularly check your blood sugar levels. This is because there is a possibility that Orlistat Tablets interfere with blood sugar levels.

Orlistat Reviews

How to order medications from us

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

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Add delivery details and complete payment process.

Price £32.99

Price Checker


Available strengths:

120 mg


Price £29.69

Includes free private prescriptions

In stock

2024/06/23 2024/06/24

Order before 15:00pm (Monday to Friday) for next day delivery