Premique Tablets is an effective HRT for menopause. Buy Premique Tablets from Click Pharmacy today, we have a wide range of HRT available.


6/15/2025 4:11:02 PM


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Premique Low-Dose Tablets

Premique is a medication used to relieve symptoms of menopause, such as hot flashes and vaginal dryness, and to prevent osteoporosis.

Medication features:

  • A short-term treatment for menopause
  • Contains medroxyprogesterone Acetate and oestrogens
  • Alleviates the symptoms of menopause

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Premique Prices

  • Medicine prices
  • Delivery Information
Medicine Quantity Price
Premique 0.3mg/1.5mg 3 months (84 tablets) £24.99

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

Royal Mail 1st Class | £3.95

Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

Find out more about our delivery service.

Refunds and returns – Read further information on return and refunds.

  • Overview
  • Directions
  • Cautions

Buy Premique Online UK

You can order Premique online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Premique

Premique is a Hormone Replacement Therapy (HRT) used to treat menopause and premenopause symptoms. It has two active ingredients, which are types of female hormones – estrogen and a progestogen (medroxyprogesterone acetate). These imitate the working of the female sex hormones oestrogen and progesterone in order to treat symptoms of menopause. It is also beneficial in helping reduce the risk of developing endometrial cancer, which is associated with taking oestrogen-only HRT in women with an undamaged uterus.

It might take a while for your body to adjust to Premique. During the initial stages, you may experience breakthrough bleeding or spotting. Since HRT should only be used as a short-term treatment for menopause, it is necessary to inform your primary physician if you experience spotting for an extended period of time.

Also, Premique is not birth control, nor will it act like one. Premique can not prevent pregnancy in women. Keep in mind that women are considered fertile until two years after their final menstrual cycle.

Premique Summary Information

Type of medicine

Menopause treatment (HRT) medication


Relieves menopausal symptoms and prevents osteoporosis

How it works

Supplies hormones to replace those the body no longer makes

Active Ingredient

Estrogen and progestogen

Directions of use

Oral tablets, typically taken once daily

Available strengths

0.3 mg/1.5 mg

Side effects

Common side effects include breast pain, tenderness and nipple discharge, muscle ache, Joint ache, fluctuation in weight.



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any menopause treatment (HRT), including Premique.

How effective is Premique

At its core, Premique is a hormone replacement therapy (HRT) designed to help relieve the symptoms of menopause. Women usually tend to go through menopause between the ages of 45 and 55. During this period of time, the ovaries tend to produce less and less oestrogen. This lack of production of oestrogen is directly responsible for halting the menstrual cycle.

Although menopause is considered a natural part of a woman's ageing process and is a part of life, it can result in symptoms that can negatively impact an individual's everyday life. There are various manifestations of the physical symptoms, which can vary depending on the person. However, the most common ones are:

  • Night Sweats
  • Hot Flashes (intense feeling of warmth, usually over the face, neck and chest)
  • Dryness in the Vagina
  • Dryness of the Eyes
  • Osteoporosis
  • Insomnia or other sleeping disorders
  • Depression
  • Mood Swings
  • Irritability or Aggravation

Such physical symptoms generally last for more than four years. However, keep in mind that these kinds of symptoms may begin several years before the menopause period starts.

How does Premique work?

Since Premique is a Hormone Replacement Therapy (HRT), it works by alleviating the symptoms of menopause by taking the levels of hormones up to a normal amount. Such hormones that the body used to produce naturally before menopause began are essential to a well-functioning body. However, some HRT medicines contain oestrogen only because the uncontrolled increase in oestrogen levels in women who still have a uterus can cause the lining of the uterus to expand significantly. As a result, the risk of endometrium cancer increases. In order to counter such risks, Premique contains progesterone.

What are the benefits of using Premique?

As we all know, starting menopause indicates decreasing levels of oestrogen. This decrease in oestrogen can lead to several symptoms, including hot flushes, night sweats, as well as vaginal dryness. Premique and Premique Low Dose are effective hormone replacement therapy treatments that help to alleviate the symptoms of menopause. This treatment is also beneficial in slowing down the development of osteoporosis. Osteoporosis can often occur after menopause – only if the other treatment has proved unsuccessful.

What does Premique contain?

There are various inactive ingredients in Premique. However, the main active ingredients within this medicine are:

  • Medroxyprogesterone Acetate (Conjugated)
  • Oestrogens (Conjugated)

How should I take Premique?

It is best to take Premique at a similar time every day. You can take the tablet with water. However, it is not necessary for you to eat something before or after. Avoid skipping doses and once the pack of Premique (28 tablets) runs out, start a new one immediately. Make sure there are no intervals. Review HRT with your primary physician every 6 months.

It is important to note that if you forget to take a tablet, for whatever reason, take it as soon as possible. This does not mean you should take two tablets at the same time. However, if the time for the next tablet has approached, then skip the missed dose.

What dosage of Premique should I take?

Premique is only available in one dose, and it is considered a relative dose low. It is known as Premique Low Dose. Each tablet of Premique Low Dose contains around 300 micrograms of conjugated oestrogen — also referred to as equine. It also consists of 1.5 milligrams of medroxyprogesterone.

Side effects

Similar to most medications, Premique may cause some side effects. However, not every person will experience these side effects, and they may even differ depending on the person. The common side effects of Premique includes:

  • Breast pain,
  • Tenderness and nipple discharge,
  • Muscle ache,
  • Joint ache,
  • Fluctuation in weight,
  • Breakthrough vaginal bleeding or spotting.

You may experience some serious side effects, as well. These include alteration in triglyceride levels and mood, complications with the heart or kidneys, blood clots, and headaches.

Warnings and cautions

Do not take Premique if you:

  • Have a blood clot or have experienced a blood clot in the past
  • Have had a heart attack or stroke recently
  • Struggle with angina pectoris
  • Have had breast cancer
  • Have had endometrial cancer
  • Have experienced endometrial hyperplasia
  • Have experienced abnormal vaginal bleeding
  • Currently have a condition which increases the risk of having a blood clot
  • Currently have a certain liver condition(s)
  • Have or had porphyria
  • Are pregnant
  • Are breastfeeding
  • Are allergic to any of the ingredients in Premique

Consult a doctor before taking Premique if you:

  • Have a family history of breast cancer
  • Have a condition that increases the risk of blood clots (such as obesity, high cholesterol, diabetes)
  • Have or had benign breast lumps
  • Have or had experienced endometriosis
  • Have or had fibroids in the womb
  • Have a family history of blood clots
  • Have a family history of high blood pressure (hypertension)
  • Have high blood pressure
  • Have or had complications with your kidneys
  • Have or had gallbladder disease
  • Experience migraines
  • Have or had systemic lupus erythematosus
  • Have or had epilepsy
  • Have or had asthma
  • Have or had otosclerosis

Cease the use of Premique and seek medical attention right away if you experience any of the following:

Blood clots: You may experience pain, swelling in the legs, and difficulty breathing.

Stroke: You may experience sudden migraines and blurred vision.

Heart disease: You may experience chest pain extending to the neck or arm (often on the left side).

Liver disease: You may notice the yellow colouration of the skin or eyes.

Premique Reviews

How to order medications from us

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

Next Day

Add delivery details and complete payment process.

Price £24.99

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Price £24.99

Includes free private prescriptions

In stock

2024/06/15 2024/06/16

Order before 15:00pm (Monday to Friday) for next day delivery