Spedra should take effect within 15 to 30 minutes for most men, one of the fastest-acting ED medicines. Buy from Click Pharmacy's discreet online service today.


6/23/2025 4:22:40 PM


Images are for illustration purposes only.

Spedra Tablets

Spedra is a prescription medication used to treat erectile dysfunction in men.

Medication features:

  • Treatment for erectile dysfunction
  • Contains the active ingredient avanafil
  • More targeted and can be faster acting

Next Day Delivery Available

UK Registered Pharmacy

Price Match Guarantee

Expected Delivery: Tuesday

If you order within: 12h36m

Spedra Prices

  • Medicine prices
  • Delivery Information
Medicine 4 tablets 8 tablets 12 tablets 24 tablets 28 tablets
Spedra 50 mg £20.99 £39.99 £57.99 £114.99 £126.99
Spedra 100 mg £25.99 £49.99 £69.99 £129.99 £144.99
Spedra 200 mg £33.99 £62.99 £99.99 £179.99 £199.99

Prices include free private prescription.

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

Royal Mail 1st Class | £3.95

Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

Find out more about our delivery service.

Refunds and returns – Read further information on return and refunds.

  • Overview
  • Directions
  • Cautions
  • FAQ

Buy Spedra Online UK

You can order Spedra online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Spedra

Spedra is a medication used to treat erectile dysfunction and increase sexual satisfaction in male adults. Erectile dysfunction is also sometimes referred to as impotence. It is characterised by the inability to get or maintain an erection firm enough for the performance of the sexual activity. Each tablet of Spedra contains the active ingredient avanafil, which belongs to the class of medications called phosphodiesterase type 5 (PDE5) inhibitors.

Spedra Summary Information

Type of medicine

Erectile dysfunction treatment


Helps in achieving and maintaining an erection

How it works

Enhances blood flow to the penis by inhibiting the PDE5 enzyme

Active Ingredient


Directions of use

Take orally, as needed, approximately 15 to 30 minutes before sexual activity with a full glass of water

Available strengths

50 mg, 100 mg, 200 mg

Side effects

Common side effects include headache, flushing, nasal congestion, dry mouth, high blood pressure



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any erectile dysfunction treatment, including Spedra.

How effective Is Spedra?

Spedra is used to provide quick relief from erectile dysfunction in men by helping achieve and maintain a firm erection suitable for sexual intercourse. It takes 15-30 minutes to take effect, and the results last for 4-5 hours. Spedra requires sexual stimulation to work; therefore, foreplay is encouraged. This medication does not cure erectile dysfunction, only provides relief and is not intended for women. Since Spedra is a prescription drug, it must be used according to the instructions provided by the doctor. Nonetheless, should you see no improvement in erections after use, speak to your doctor or a health practitioner?

How does Spedra work?

Spedra contains the active ingredient avanafil, known as a phosphodiesterase type 5 (PDE5) inhibitor. This drug works by inducing smooth muscle relaxation in the spongy erectile tissue of the penis, known as the corpus cavernosum. This allows increased blood flow to the erectile tissue, filling it and causing a firmer and longer-lasting erection

Spedra inhibits the activity of the enzyme phosphodiesterase type 5 (PDE5), which as a result, increases the amount of the chemical substance cGMP in the spongy tissue of the penis. cGMP is responsible for the physiological change of smooth muscle relaxation and increasing the inflow of blood in the erectile tissue.

Alternative treatments to Spedra

The effects of Spedra may vary from person to person, which is why one needs to turn to alternative treatments if Spedra proves to be ineffective for you. For the treatment of erectile dysfunction, you can take Cialis (tadalafil), Viagra (sildenafil), and Levitra (vardenafil) instead of Spedra. However, you should consult your GP before switching. All of the mentioned alternative medications are available in various strengths and pack sizes.


How should I take Spedra?

In male adults, the recommended dose of Spedra is 100 mg taken orally once when needed. Your doctor may prescribe a lower dose at the start and increase afterwards if required. 

The dose should be taken 15-30 minutes before you plan on having sexual intercourse. Spedra can be taken with or without food, although it works best on an empty stomach. Sexual stimulation is required for the drug to work. You must not take Spedra more than once per day. 

Dose adjustments may be required in case Spedra is used along with other medications. Do not take more or less than the prescribed dose. If symptoms persist or worsen, get in touch with your doctor or a pharmacist at Click Pharmacy.

What dose should I choose?

Spedra is available in 3 dosages: 50 mg tablets, 100 mg tablets and 200 mg tablets. Each pack of Spedra contains 4 tablets. You can purchase the pack online, and it will be sent directly to you by Next Day Delivery via Click Pharmacy.

The dose you should take depends on the prescription. Check the patient leaflet enclosed in the medication before use, and make sure that you adhere to the instructions provided. 

This medication is not suitable for individuals under the age of 18 years.

How long do I take Spedra before I notice a difference?

Take Spedra exactly as prescribed. It should be used on an as-needed basis, no more than once per day. Depending on your dose, wait for the medication to take effect within 15-30 minutes. Your doctor or the pharmacist will prescribe the lowest dose that suits you.

Side effects

Like all medicines, you may or may not experience any of the following side effects by taking Spedra. Some of these include:

  • Flushing

  • Headache

  • Nasal congestion

  • Sinus congestion

  • Feeling very tired or sleepy

  • Hot flushes

  • Increased heart rate

  • Palpitations

  • Back pain

  • Blurry vision

  • Indigestion

  • Raised liver enzymes

  • High blood pressure

  • Premature ejaculation

  • Dry mouth

  • Insomnia

  • Muscle spasms

  • Swelling in the feet or ankles

  • Heartburn or stomach pain

Discontinue use immediately and seek emergency medical help in case you experience any of the following serious side effects:

  • Priapism: an uncommon condition in which an erection will not go away. If your erection has not subsided in over 4 hours, seek medical attention immediately, or it can cause permanent damage to your penis. 

  • Sudden decline or loss of vision in one or both eyes

  • Blurred vision

  • Sudden decline or loss of hearing, sometimes paired with dizziness or ringing in the ears. 

If you experience an allergic reaction to the medication, characterised by swollen eyelids, face or lips, chest pains and tightness, difficulty breathing, dizziness, fever, or an itchy rash, seek immediate medical attention from your GP or hospital. 

Be cautious if you experience mouth ulcers, unexplained bruising, a sore throat, extreme paleness, fever, weakness, or exhaustion. These signs are associated with blood disorder conditions such as anaemia, low platelet count, low white blood cells, suppressed bone marrow, or reduction in agranulocytes. 

Speak to your doctor or consult our pharmacist at Click Pharmacy should you require any further advice.

When shouldn’t I take Spedra?

Do not begin this medication if you are allergic to avanafil, other PDE5 inhibitors (Viagra, Levitra, etc.) or any other ingredients listed on the product. In case you are on other medications, whether prescribed, herbal, or over-the-counter medications, discuss with your doctor before taking Spedra. 

This advice is even more crucial to people taking medicines such as nitrates, alpha-blockers, antibiotics (such as erythromycin), primidone, phenobarbital, carbamazepine, riociguat, verapamil, amprenavir, aprepitant, fluconazole, diltiazem, ritonavir, fosamprenavir and quinidine, amiodarone, and other medicines used for the treatment of arrhythmias (irregular heart rate).

What is the difference between Spedra Tablets and Viagra Tablets?

While both Spedra Tablets and Viagra Tablets are effectively used for the treatment of erectile dysfunction, the main difference is the ingredients. The active ingredient in Spedra Tablets is avanafil, whereas the active ingredient in Viagra Tablets is sildenafil.

Spedra Reviews

How to order medications from us

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

Next Day

Add delivery details and complete payment process.

Price £20.99

Price Checker


Available strengths:

50 mg 100 mg 200 mg


Price £20.99

Includes free private prescriptions

In stock

2024/06/23 2024/06/24

Order before 15:00pm (Monday to Friday) for next day delivery