Wegovy vs. Saxenda: A Simple Comparison

Overview of GLP-1 Receptor Agonists

Wegovy and Saxenda are medications used to help with weight loss. They work in similar ways but have some differences.

Wegovy (Semaglutide)

  • Active Ingredient: Semaglutide

  • Use: Helps adults and kids over 12 who are obese or overweight.

  • How to Use: Weekly subcutaneous injection (injection is given in the fatty tissue, just under the skin).

  • Benefits: Reduces appetite by acting on GLP-1 receptors in the brain, helping to eat less and lose weight (Drugs.com, 2024).

Saxenda (Liraglutide)

  • Active Ingredient: Liraglutide

  • Use: Approved for weight loss in adults and certain younger individuals.

  • How to Use: Daily subcutaneous injection.

  • Benefits: Slows digestion and makes you feel full longer, which helps to eat less (Drugs.com, 2024).

Comparison Table




Primary Use

Weight management for adults and teens

Weight management for adults and some teens


Approved for chronic weight management

Approved for weight management

Dosage Form

Weekly subcutaneous injection

Daily subcutaneous injection

Key Benefits

Reduces appetite, aids in long-term weight management

Reduces appetite, aids in gradual weight loss

Side Effects


Nausea, diarrhea, constipation, abdominal pain

Nausea, diarrhea, constipation, risk of thyroid tumors


Not approved for treating diabetes

Not for treating diabetes, different dosages from Victoza

Practical considerations and prescription advice

Choosing between Wegovy and Saxenda

The choice depends on how often you want to take it and your health needs.

Side effects and safety

Both drugs can cause stomach problems. Saxenda has a risk of thyroid tumors, so it needs careful watching.

Cost and accessibility

Saxenda usually costs less but needs daily injections, which might be less convenient than Wegovy's weekly injections.


Talk to a healthcare provider to choose between Wegovy and Saxenda. Consider your health, weight goals, and lifestyle.

Additional resources

For more info on Wegovy and Saxenda, check out:

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