Wegovy vs. Ozempic: Detailed Comparison

Overview of Semaglutide-based medications

Semaglutide is the active ingredient in both Wegovy and Ozempic. It works on the GLP-1 receptors but targets different conditions.

Wegovy (Weight management)

  • Approved for: Chronic weight management.

  • Who can use it: Adults and teenagers aged 12+ who are obese or overweight with health issues.

  • How it works: It acts like GLP-1 to control appetite and insulin, making you feel full and helping with weight loss.

  • How to use: One injection under the skin each week (Drugs.com, 2024).

Ozempic (Diabetes treatment)

  • Approved for: Managing type 2 diabetes and reducing the risk of major cardiovascular events in diabetic patients.

  • Who can use it: Adults with type 2 diabetes, especially those at risk of heart issues.

  • How it works: It boosts insulin production and suppresses glucagon release to control blood sugar.

  • How to use: One injection under the skin each week (Drugs.com, 2024).

Detailed comparison table




Primary use

Weight management for obese or overweight individuals

Control of blood sugar levels in type 2 diabetes

MHRA approval

Approved for weight loss

Approved for type 2 diabetes treatment and heart risk reduction

Dosage form

Injection under the skin, once a week

Injection under the skin, once a week

Key benefits

Reduces appetite, enhances insulin production

Lowers blood sugar, reduces cardiovascular risks


Not for diabetes treatment

Not approved for primary weight loss but may help reduce weight

Practical considerations and prescriptions

  • Prescription Advice: Both medications need a prescription and should be used under a healthcare provider's supervision. The choice depends on the patient’s health needs and history.

  • Side Effects and Safety: Both drugs may cause side effects like nausea, vomiting, diarrhea, abdominal pain, and constipation. Their long-term safety is continuously reviewed.

  • Cost and Accessibility: Costs can vary based on insurance and location. Patients should consult healthcare providers to find the most affordable and suitable option.


Choosing between Wegovy and Ozempic should be based on specific health goals and conditions, with advice from healthcare providers. Both medications use semaglutide to address major health issues effectively.

Resources for further reading

For more information on Wegovy, Ozempic, and their medical uses, check these resources:

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