What is the difference between Imigran and Sumatriptan?

Sumatriptan and Imigran are two medications that are to provide relief from migraine headaches. While they both contain the same active ingredient, there are differences between the two medications.

What is Imigran?

Imigran is a medication that is designed to treat migraines. Its active ingredient is Sumatriptan, which reduces inflammation in the brain's blood vessels. GlaxoSmithKline manufactures Imigran, and it is available in tablet form and nasal spray. The tablets are generally taken at the onset of a migraine headache and can provide relief within 30 minutes to an hour. Imigran is available in several dosages, ranging from 50 to 100mg tablets.

What is Sumatriptan?

Sumatriptan is the generic name for the active ingredient in Imigran. Like Imigran, Sumatriptan is designed to treat migraines by reducing inflammation in the brain's blood vessels. Unlike Imigran, Sumatriptan is available in different, including tablets, nasal sprays, injectable solutions, and transdermal patches. Sumatriptan is available in several dosages, ranging from 25 to 100mg tablets. The dosage depends on the severity of the patient's migraine and other medical factors.

How do Imigran and Sumatriptan work?

Imigran and Sumatriptan work by targeting the serotonin receptors in the brain. During a migraine, serotonin levels in the brain drop, triggering inflammation in the blood vessels. Imigran and Sumatriptan help restore serotonin levels in the brain, reducing inflammation and alleviating migraine symptoms.

What are the differences between Imigran and Sumatriptan?

The following are the main differences between the two medications:

Brand vs Generic

The main difference between Imigran and Sumatriptan is that Imigran is a brand-name medication, while Sumatriptan is the generic version. Imigran is manufactured by GlaxoSmithKline, while Sumatriptan can be manufactured by any company with the appropriate licensing.


Imigran is only available in tablet form and nasal spray, while Sumatriptan is available in several different formulations. The various formulations of Sumatriptan can provide patients with more options when administering the medication. For example, patients with difficulty swallowing pills may prefer a nasal spray or injectable solution.


Imigran and Sumatriptan are available in several dosages, depending on the severity of the patient's migraine headaches and other medical factors. Therefore, patients should work with their doctor to determine the appropriate dosage and not exceed the recommended dosage without medical supervision.


Imigran and Sumatriptan are priced differently due to their manufacturing and marketing differences. As a result, Imigran is more expensive than Sumatriptan.

Which medication is better?

The decision of which medication to use will depend on various factors, including the patient's medical history, the severity of their migraine, and their preferences for medication. In general, Imigran and Sumatriptan are equally effective at treating migraine.

If a patient prefers a tablet form of medication or has been successfully treated with Imigran in the past, then Imigran may be the preferred choice. However, if a patient chooses a different drug or seeks a more cost-effective option, Sumatriptan may be better.

Ultimately, the decision of which medication to use should be made in consultation with a doctor, who can evaluate the patient's medical history, symptoms, preferences, and recommendations based on their clinical expertise.


Imigran and Sumatriptan are both effective medications for treating migraine headaches. Although they contain the same active ingredient, their formulations, dosages, and prices differ. Patients should consult with their doctor to determine which medication is best for their needs. With the proper medication and treatment plan, patients can manage their migraines and enjoy a better quality of life.

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