Circadin (Melatonin) is commonly used to overcome Jet Lag. Get your sleeping clock in order and buy Circadin tablets safely and securely from Click Pharmacy today.


6/23/2025 4:45:44 PM


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Circadin Tablets

Circadin is a sleep aid medication used to treat insomnia.

Medication features:

  • A prescription-only medicine
  • The only licensed melatonin medication available in the UK
  • Can be taken to assist with insomnia

Next Day Delivery Available

UK Registered Pharmacy

Price Match Guarantee

Expected Delivery: Tuesday

If you order within: 12h36m

Circadin Prices

  • Medicine prices
  • Delivery Information
Medicine Quantity Price
Circadin 2mg 10 Tablets £19.99
Circadin 2mg 20 Tablets £35.98
Circadin 2mg 30 Tablets £53.97

Delivery charges

Orders approved by our medical team before 3pm Monday – Friday are dispatched the same day via Royal mail. All orders are sent using a tracked and signed for service. Orders are not dispatched on weekends and bank holidays.

Royal Mail 1st Class | £3.95

Delivered within 1-3 working days. Excludes bank holidays. A tracked service with signature required on delivery.

Royal Mail Special Delivery Guaranteed before 1pm | £6.95

Delivered within 1 working day before 1pm. Excludes Sundays and bank holidays. A tracked service with signature required on delivery.

Find out more about our delivery service.

Refunds and returns – Read further information on return and refunds.

  • Overview
  • Directions
  • Cautions
  • FAQ

Buy Circadin Online UK

You can order Circadin online in the UK from our registered pharmacy. Complete the online medical assessment to be reviewed by one of our prescribers. If approved, your medication will be dispensed by our pharmacy team for next day delivery to your address. 

About Circadin

Circadin (Melatonin) is a prolonged release melatonin supplement which can be taken to assist with insomnia and, after the positive effects on jet lag were studied in the Cochrane Review, it can also be used by anyone suffering from sleep issues after changes in time zones due to long flights.

The hormone melatonin is released naturally from the pineal gland during the evening and through the night to help you get to sleep, and stay asleep whilst it is dark. During the day when it is light, melatonin production is suppressed, and this is how the body regulates its sleep/wake cycle.

After crossing into different time zones, the time you would normally start thinking about going to bed, around 8 pm or 9 pm, may now be the middle of the afternoon or night in the country you have travelled to. As such, your body clock becomes confused as at first, melatonin still naturally begins to be produced around the same time as normal. This is your normal circadian rhythm which is a twenty four hour cycle during which physiological processes naturally occur such as going to sleep and waking up. You can wait until your jet lag passes naturally and your body gets back in line with its new time zone, but this can take several days. As such, some people find enormous benefit in using a melatonin supplement to help top up the body when it is not producing this hormone at the right time, or enough of it, to induce sleep.

Circadin Summary Information

Type of medicine

Sleep aid medication


Treats insomnia

How it works

Regulates sleep-wake cycle

Active Ingredient


Directions of use

Oral, once daily before bedtime

Available strengths

2 mg

Side effects

Common side effects include Irritable, nervous, restless, anxious, nauseous, weak, dizzy or lethargic.



The information provided in the summary table is for reference only. It is important to consult a qualified healthcare professional before starting any jet lag treatment, including Circadin.

How effective is Circadin?

In trials, Circadin was shown to effectively secrete melatonin over several hours, which enabled patients to enjoy a natural sleep cycle despite disturbances due to external influences such as jet lag.

When you are shifting between time zones, one study also showed that small doses of melatonin, such as that found in Circadin, can help travellers overcome jet lag more quickly and with fewer issues. This could account for why 1.3% of American adults take melatonin for jet lag and other sleep disorders, a number which more than doubled between 2007 and 2012.

Why choose Circadin?

Circadin is presently the only licensed melatonin medication available in the UK, and although other quick-release products are available online, they are not licensed here. It has been shown that these quick-release products can affect blood pressure negatively, causing it to peak, whereas Circadin offers a gentle, slow release of melatonin throughout the course of several hours, which helps your body clock to safely, naturally and effectively get itself back on track, easing sleep issues such as jet lag and insomnia.

What is contained in Circadin?

Circadin’s active ingredient is melatonin.

The inactive ingredients include:

  • Ammonio methacrylate copolymer type B
  • calcium hydrogen phosphate
  • lactose
  • colloidal anhydrous silica,
  • purified talc
  • magnesium stearate

Tell your doctor if you know you suffer with allergies to any of the above.

How does Circadin work?

Once taken, the formulation releases melatonin steadily for anywhere up to 10 hours, allowing you to enjoy a natural sleep pattern during this time. It helps by adding an external source of melatonin to the natural source already secreted from your pineal gland, which may be limited in someone suffering with jet lag or insomnia. This additional melatonin facilitates a sense of tiredness, eases the ability to get to sleep and stay asleep and improves the overall quality of sleep, which in turn helps patients experience a better quality of life overall.


How should I take Circadin?

It is advised that patients take Circadin after a light meal and around 1 to 2 hours before bed, which is roughly the same time your pineal gland would naturally begin to produce melatonin to help you begin to feel tired. A quicker release of the active ingredient will occur if taken on an empty stomach.

Follow the instructions in the patient leaflet and/or any recommendations given to you by your GP, or Click Pharmacy doctor for best results.

What are the side effects of Circadin?

Some people may find that they experience certain side effects when using Circadin though it is considered to be unlikely. As when starting to take any medication, it is important to remain vigilant and aware of any changes with your health. If you notice any of the following and find them to be affecting your health or worrying you in any way, speak to your doctor or pharmacist to get advice.

The following have been known to occur in around 1 in 100 patients, which is medically considered to be ‘uncommon’ so do not be alarmed by this list:

  • Feeling: irritable, nervous, restless, anxious, nauseous, weak, dizzy or lethargic.
  • Experiencing: chest pain, insomnia, abnormal dreams and nightmares, migraines and headaches, high blood pressure, (upper) abdominal pain, indigestion, mouth ulcers, jaundice, night sweats, pruritis, itching, rashes, dry skin, pain in extremities or menopausal symptoms.

Different people will have a unique reaction to the medication, so tell your doctor if you notice any of the above or any other issues as soon as possible.

Can I drive after taking Circadin Tablets?

No, you should not drive or operate machinery after taking Circadin Tablets. This is because the active ingredient, melatonin, controls the sleeping pattern making you feel sleepy. This makes it unsafe to drive or operate machinery, as these activities require full concentration.

Can pregnant or breastfeeding women take Circadin Tablets?

Due to the lack of research, it is advised that pregnant or breastfeeding women do not take Circadin Tablets. This is because there has not been enough research to see whether the active ingredient, melatonin, affects the baby in any way.

Circadin Reviews

How to order medications from us

Order your medication in a few clicks. Our process is easy, fast and secure.

Step 1

Short Medical Assessment

Fill out a questionnaire so our prescriber can assess if the treatment is suitable for you.

Step 2

Select Preferred Medication

Choose the medication you require from the range offered by our online pharmacy.

Step 3

Next Day

Add delivery details and complete payment process.

Price £19.99

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Price £19.99

Includes free private prescriptions

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Order before 15:00pm (Monday to Friday) for next day delivery