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As well as the difficulty in maintaining or getting an erection, erectile dysfunction (ED) can also result in a lowering of desire for sexual intercourse, premature ejaculation, delayed ejaculation or the inability to achieve an orgasm despite stimulation.
Tadalafil entered the market in 2003 under the brand name Cialis and quickly became a popular option for men suffering with this issue.This is because the effects of tadalafil has been found to last anywhere from 36 to 72 hours, allowing the user to engage in sexual activity and ensure a firm and easily maintainable erection without worry.
Studies show tadalafil increases the flow of blood to the penis, and it is this accumulation of blood which causes an erection. The medication relaxes the veins to the penis and allows a man to achieve and keep his erection, enabling him to be effectively stimulated and have intercourse.
The most effective starting dosage is often recommended at 10mg to be taken before sexual intercourse. The medication remains active in your system for up to 2 days allowing you to have sex as and when you please during this time.
Certain substances are created during sexual stimulation including nitric oxide, cGMP and phosphodiesterase type 5 or PDE5. In men with ED, the PDE5 destroys the cGMP which is what contracts blood vessels carrying the blood, helping to keep the erection firm. When cGMP is removed in this way, the blood vessels return to normal, and in turn the erection is lost. Tadalafil is a PDE5 inhibitor and has been found to effectively stop the destruction of cGMP from occurring, thus allowing the user to retain his erection effectively.
Many men prefer to use tadalafil as, when taken daily, it enables them to have sex more spontaneously, just as they would without medication. Another great benefit of tadalafil over other forms of ED medication is how long it remains active in the body for; in some cases for up to 3 days.
For many men, ED can cause high levels of stress and anxiety and as such, easing the symptoms through the use of medication such as tadalafil. It can reduce their worry and when this happens, the amount of ED occurrences can naturally decrease as it is happening because of emotional concerns such as stress at work, or due to the impotence itself.
It has also been shown to increase the intravaginal ejaculatory latency time, or the time taken to ejaculate during penetration, by up to two and half minutes.
You can buy Tadalafil online via Click Pharmacy simply and quickly and have it sent to your chosen address discreetly. Some patients prefer to speak to their GP before purchasing their prescription online to ensure they have the correct dosage, but you may be more comfortable booking an appointment with one of Click pharmacy’s doctors and speak to someone online.
You will be asked to fill in a health questionnaire so our pharmacists can confirm that this is the correct medication for your situation and to ensure it will be safe for you to use based on your current health. Once a positive assessment is made you can purchase your prescription and it will be sent to you via next day delivery.
The active ingredient in each tablet is tadalafil which comes as 2.5mg, 5mg, 10mg or 20mg.
The inactive substances are:
As with any medication, it is to be taken as prescribed by your doctor or as advised by your pharmacist though you are not to take more than one per day. It is recommended that you take it whole, with water and with or without food though often it is more effective when taken on an empty stomach. Eating grapefruit or drinking its juice can make tadalafil more potent and therefore potentially dangerous; as such, it is only to be consumed with caution.
Your doctor will advise you of the best way to take the medication, though there are 2 main ways to do so:
This would need to be discussed with your doctor because dosage and the regularity with which you take it would be based on any underlying health issues.
Known as a PDE5 inhibitor, the medication helps to treat erectile dysfunction by allowing a man to achieve and keep an erection. It does so by keeping the blood vessels leading to, and within the penis relaxed, allowing plenty of blood to flow causing firmness.
By inhibiting the enzyme PDE5, which destroys a substance released during sexual activity known as cGMP which is designed to regulate the flow of blood to the penis, thus keeping it firm, means tadalafil is found to be a highly effective option for many men.
An individual’s reaction to any medication is always unique, so whilst one person may need only a lower dose of a drug to see the benefits, another may require a stronger dose of something else. In other words, tadalafil may work better for one patient over sildenafil as there are notable differences.
Both tadalafil and sildenafil are the generic forms of the medication used in branded tablets, Cialis and Viagra respectively and whilst tadalafil entered the market in 2003. Other differences include:
In studies of up to 2 years, tadalafil was found to be safe and effective in doses of 5 to 20mg either taken as needed or on a daily basis.
Due to tadalafil’s prolonged release half-life, up to 5mg may be prescribed to be taken daily meaning the drug remains at a steady level in the body, thus separating medication from sexual intercourse and enabling the user to have sex as and when desired. It needs to be taken once a day at the same time and in the case of the daily tablet, preferably on an empty stomach. Anything more than a small wine or beer is not advised before taking your tablet as it can affect your ability to get an erection, thus causing it to work counteractively against the medication. Mixing alcohol with the drug can also increase the risk of hypotension.
The daily dose is usually 2.5mg but can be as much as 5mg in some cases, though this will be discussed with your doctor before beginning a prescription. It can take around 4 to 6 days for the drug to build up in your system, after which you will respond to sexual stimulation as usual.
In many cases, patients taking a lower daily dose also found that they suffered fewer or more minor forms of the potential side effects experienced in comparison to the higher dosage.
The most common side effects of the drug include stomach pain, muscles aches, a blocked nose or a headache.
Certain issues which occur during sexual intercourse are considered to be more serious and include sickness and nausea, dizziness and numbness or tingling anywhere in the upper body including down the arms. Over the course of 2+ months as it can signify more serious health problems such as cardiovascular disease, diabetes or hypertension.
In very rare cases, tadalafil can affect the blood flow to the optic nerve causing usually short term, sudden visual impairment. If this happens, discontinue the treatment and seek medical help.
Tadalafil cannot be taken along side certain drugs including nitrate prescriptions for heart issues as this can lead to a dangerous drop in blood pressure.
There are several other drugs including anti-fungals, antidepressants, antibiotics and barbiturates which are not recommended to be taken alongside tadalafil. A more extensive list can be found here and you can discuss this further with your health practitioner prior.
An erection which will not go away after several hours can be particularly dangerous and can cause long-term damage. This is known as priapism and requires immediate medical attention.
Content reviewed 06 April 2020, Last updated 06 April 2020