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Malarone is the brand name for a combination of drugs called atovaquone and proguanil. It’s used in the treatment and prevention of malaria, a potentially fatal disease caused by parasites passed on from female mosquitoes which carry the malaria infection. The mosquitoes pick up the infection from the blood of infected humans, so protecting yourself from malaria can also help to stop the spread of malaria in the areas you are travelling in.
Atovaquone doesn’t work on its own; as such it’s always paired with proguanil for optimum results as they work in two separate ways to stop malarial parasites in the blood stream from reproducing and developing.