Emtricitabine/Tenofovir Tablets

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Emtricitabine/Tenofovir Tablets

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  • Overview
  • FAQ
  • Side Effects
  • Information leaflet
  • Reviews

What is Emtricitabine/Tenofovir Tablets

Emtricitabine/Tenofovir (Generic Truvada) PrEP treatment was launched in 2012 and became available on the NHS in 2017.  It is a daily pill combining two drugs which, when taken before exposure to the human immunodeficiency virus (HIV), can help prevent the risk of infection if the body does come into contact with a carrier.  It is the first pharmacological option on the market for this purpose and is now used widely around the world for daily use.  In 2015, the World Health Organisation (WHO) recommended the drug for those who are at substantial risk of infection.

How long can I take Emtricitabine/Tenofovir (PrEP) for?

Emtricitabine/Tenofovir is safe to take as a daily tablet whilst the risk of exposure to HIV is high.  Whilst studies are still being performed on the risks of long term use of this medication, experts seem confident that certainly short term use, (in one study, up to 48 weeks) is perfectly safe. 

How effective is Emtricitabine/Tenofovir (PrEP)?

Studies show that Emtricitabine/Tenofovir works 99% of the time if you take it every day without fail.  When taken on average 4 times a week, this drops to 96%.  The protection for taking 2 tablets per week drops substantially to just 76% which shows that when taken as guided it can have a very positive outcome for anyone in danger of catching the virus.  

Patients should note that the WHO has asserted that it takes 7 days from beginning the treatment before there are high enough levels of the drug in the bloodstream for full protection during possible anal transmission.  The US Centres for Disease Control and Prevention (CDC) state that 20 days is required for HIV exposure from the injection of drugs and for women who are at risk due to vaginal sex transmission.  

How should I take Emtricitabine/Tenofovir (PrEP)?

You should always read the patient leaflet which comes with any medication before beginning a new treatment and take your doctors advice for use.  If you have any queries or concerns, ask your GP or Click Pharmacy doctor before proceeding.

Emtricitabine/Tenofovir is taken by mouth once a day, with or without food.  You will be given the dosage most appropriate for you based on issues such as any current medical conditions, your response to treatment and your kidney function.  In some cases, the dosage is also based on a patients weight.

It is recommended that you take PrEP at the same time each day thus keeping the level of drug in the blood steady and giving you as much protection as possible.  Taking more or less can be harmful and stop the medication from working as effectively.  If you wish to stop treatment, then speak to your doctor for advice on how to taper off.

How does Emtricitabine/Tenofovir (PrEP) work?

Emtricitabine/Tenofovir is designed to stop the virus from being able to enter and overtake healthy cells within the body due to the presence of these drugs in the bloodstream.  It is an antiretroviral drug, or ARV, which works by inhibiting certain enzymes required by the virus to replicate itself and take a hold.  In this case, the reverse transcriptase enzyme is predominantly halted in its replication, along with the integral and protease enzymes.  Due to the virus’s ability to adapt itself and become resistant to drugs, a combination is used to keep it at bay.  By taking Emtricitabine/Tenofovir, the immune system is able to repair itself thus preventing further longterm damage as the virus loses its hold on the body.

It is crucial you take an HIV test to determine whether or not you are HIV negative before beginning PrEP.  If infected, the virus requires more than these two drugs to be stemmed.  You will also build up a resistance to both Emtricitabine and Tenofovir if you take PrEP whilst HIV positive without other medications making them ineffective and allowing the virus to become more established.

Taking PrEP after exposure will not protect you from developing the virus.  In this instance, you require Post Exposure Prophylaxis treatment, or PEP.

Can I buy Emtricitabine/Tenofovir (PrEP) Online?

Emtricitabine/Tenofovir is a prescription-only medication so you will be asked to fill in a medical questionnaire for our doctors to assess before approving you for treatment.  Once approved you will be given a prescription and from there you can purchase PrEP online via Click Pharmacy.  It will be sent quickly and discreetly direct to your chosen address by next day delivery where possible.  If you prefer, you may book a Skype or email appointment with one of our doctors to further discuss your medical situation.  The appointment will be private and totally confidential.

Once you have your prescription you will be able to buy your medication again without redoing the health assessment.

Why choose Emtricitabine/Tenofovir (PrEP)?

The reason many people, both male and female, choose to take Emtricitabine/Tenofovir is that it works to protect them from the risks of HIV.   It has also been found in studies to have no significant side effects and for anyone who does suffer from mild issues, they find that they clear up within the first month of taking the drug.

The CDC’s guidelines show that the drug is most commonly recommended for:

  • men who have sex with men
  • men and women who have regular sex with an HIV positive partner
  • sex workers
  • those who inject drugs
  • transgender women

It is becoming more and more widely known about, used and trusted and in the US, there is a 10 year initiative underway, rolling out the use of PrEP for those in high-risk situations.  According to the AVAC’s PrEP Watch database, as of January 2020, nearly 160,000 people in America were trusting PrEP to protect them from the risk of HIV with numbers set to rise.

What is contained in Emtricitabine/Tenofovir (PrEP)?

The active ingredients found in PrEP are emtricitabine and tenofovir which are both seen to inhibit the enzyme in the HIV virus which causes it to be able to establish itself within the body.

The following list are the inactive ingredients which make up this fixed-dose combination tablet:

  • croscarmellose sodium
  • lactose monohydrate
  • magnesium stearate
  • microcrystalline cellulose
  • pregelatinized starch (gluten free).

If you are lactose intolerant, please let your GP or Click Pharmacy doctor know in advance of beginning this treatment.

What are the side effects of Emtricitabine/Tenofovir (PrEP)?

A wide number of patients using this medication will not experience any side effects, and those that do find they are usually mild and stop after around 4 weeks of use.  It is important to note that if you have been prescribed PrEP, then any side effects from it will be outweighed by the risks of becoming infected with HIV.

Side effects may include:

  • diarrhoea, stomach pains or bloating
  • headaches and dizziness
  • insomnia
  • feelings of weakness within the body
  • rash

If you wish to you, you can keep in contact with your doctor if you experience any such side effects.

  • Less common but more serious side effects can include
  • jaundice
  • discoloured or itchy eyes
  • stiffness in the joints
  • lactic acidosis
  • anaemia

If you experience any of these side effects, seek medical attention right away.  Also, if you are taking other medication, let you doctor know before beginning this treatment.

What are the side effects of Emtricitabine/Tenofovir (PrEP)?

A wide number of patients using this medication will not experience any side effects, and those that do find they are usually mild and stop after around 4 weeks of use.  It is important to note that if you have been prescribed PrEP, then any side effects from it will be outweighed by the risks of becoming infected with HIV.

Side effects may include:

  • diarrhoea, stomach pains or bloating
  • headaches and dizziness
  • insomnia
  • feelings of weakness within the body
  • rash

If you wish to you, you can keep in contact with your doctor if you experience any such side effects.

  • Less common but more serious side effects can include
  • jaundice
  • discoloured or itchy eyes
  • stiffness in the joints
  • lactic acidosis
  • anaemia

If you experience any of these side effects, seek medical attention right away.  Also, if you are taking other medication, let you doctor know before beginning this treatment.

What are Emtricitabine/Tenofovir Tablets used for?

Emtricitabine/Tenofovir Tablets are used as a pre-exposure prophylaxis to infections such as HIV.

Can children use Emtricitabine/Tenofovir Tablets?

Emtricitabine/Tenofovir Tablets are not suitable for anyone under the age of 18 years old.

Do I need a prescription to buy Emtricitabine/Tenofovir Tablets?

Yes, you require a prescription to purchase Emtricitabine/Tenofovir Tablets. After completing a short online questionnaire on our website, you will be provided with a prescription allowing you to purchase Emtricitabine/Tenofovir Tablets.

Can men use Emtricitabine/Tenofovir Tablets?

Yes, Emtricitabine/Tenofovir Tablets are suitable for use by both men and women.

How effective are Emtricitabine/Tenofovir Tablets?

Emtricitabine/Tenofovir Tablets are up to 99% effective if taken everyday.

If you only take Emtricitabine/Tenofovir Tablets 4 times a week, the effectiveness decreases to 96%.

What is the active ingredient in Emtricitabine/Tenofovir Tablets?

The active ingredients in Emtricitabine/Tenofovir Tablets are Emtricitabine and Tenofovir. These ingredients are effective at preventing one from catching the infection despite making contact with the carrier.

How should I take Emtricitabine/Tenofovir Tablets?

For maximum protection it is advised to take Emtricitabine/Tenofovir Tablets once everyday.

Can I take Emtricitabine/Tenofovir Tablets if I have any kidney problems?

If you suffer from any kidney problems, it is advised to consult with a GP or pharmacist before you take Emtricitabine/Tenofovir Tablets.

Can pregnant or breastfeeding women take Emtricitabine/Tenofovir Tablets?

Pregnant or breastfeeding women should refrain from using Emtricitabine/ Tenofovir Tablets unless it is the only treatment available.

Does taking Emtricitabine/Tenofovir Tablets affect my ability to drive or operate machinery safely?

A common side effect from using Emtricitabine/Tenofovir Tablets is feeling dizzy. If you experience any dizziness you should refrain from driving or operating machinery until you are fit again.

Can I drink alcohol while using Emtricitabine/Tenofovir Tablets?

You should refrain from drinking alcohol while using Emtricitabine/Tenofovir Tablets. This is because a common side effect is dizziness, drinking alcohol can worsen these side effects.

Can I take other medication with Emtricitabine/Tenofovir Tablets?

You should consult with a GP or pharmacist, as using Emtricitabine/Tenofovir Tablets may interact with other medications. For example if you are taking atazanavir, you may need to be prescribed another drug.

Can I combine different drugs to prevent me from HIV infection?

You should always consult with a GP or pharmacist before combining different drugs, especially for the same treatment as they may contain the same ingredients.

What is the difference between Emtricitabine/Tenofovir Tablets and Truvada?

While they are effectively used for the same treatment, the main difference is price and branding. Truvada is the branded version of Emtricitabine/Tenofovir Tablets, making it more expensive.

You may experience a number of side effects after using Emtricitabine/ Tenofovir Tablets. Common side effects include:

  • Nausea
  • Headaches
  • Back pin
  • Change in colour of skin on palms
  • Diarrhoea
  • Dizziness
  • Sleepiness

If any of these symptoms worsen, you should stop using Emtricitabine/ Tenofovir Tablets and seek medical advice as soon as possible.

Always read the patient information leaflet before starting your treatment. The patient information can be found here.

Authored by Jana Abelovska

Last reviewed 20 April 2021

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